Alfredo Butternut Squash Pasta Bake

Featured in: Classic Family Dinners

Savor creamy Alfredo blended with roasted butternut squash and perfectly cooked pasta, finished with bubbling cheese on top. Layers of rich sauce, tender vegetables, and golden mozzarella offer delightful flavors in each bite. Ideal for family dinners or gatherings, this dish brings hearty comfort and Italian-American flair to the table. Enjoy easy preparation and satisfying results—just toss, bake, and serve warm, optionally garnished with fresh parsley for a bright finish.

Updated on Sat, 25 Oct 2025 08:54:21 GMT
Golden Alfredo Butternut Squash Pasta Bake bubbling in a dish, ready for a comforting meal. Pin
Golden Alfredo Butternut Squash Pasta Bake bubbling in a dish, ready for a comforting meal. | panpatriot.com

This Alfredo Butternut Squash Pasta Bake is my family’s go-to when comfort food is needed on a chilly night. Tender roasted butternut squash and pasta are cloaked in a silky homemade Alfredo sauce, then baked until bubbly and golden. The result is a cheesy, creamy dinner that feels like a warm hug, whether you are gathering friends or settling in for a cozy evening.

When I first tested this during a quiet Sunday in autumn, my whole kitchen was full of buttery aroma and deep squash sweetness. Even my pickiest kid asked for seconds and now it is a regular on our table.

Ingredients

  • Penne or rigatoni pasta: Good quality bronze-cut varieties hold sauce better and will not turn mushy
  • Butternut squash: Choose a medium squash that feels heavy for its size and has unblemished skin for sweetness and creaminess
  • Garlic and yellow onion: Fresh garlic and sweet onion build strong flavor in the sauce base
  • Olive oil: Use extra virgin for best flavor on the roasted squash
  • Unsalted butter: Starting with real butter gives Alfredo its signature richness
  • All-purpose flour: This thickens the Alfredo sauce for that creamy texture
  • Whole milk and heavy cream: For a lusciously rich and smooth sauce with structure
  • Fresh Parmesan cheese: Always grate your own for best melting and flavor impact
  • Salt black pepper and nutmeg: The essentials for balance and warmth a little nutmeg makes all the difference
  • Mozzarella cheese: Melts beautifully for a gooey cheesy topping
  • Fresh chopped parsley: Adds a burst of color and freshness and brightens the finished dish

Instructions

Prep the Oven and Baking Dish:
Preheat your oven to 200 degrees Celsius 400 degrees Fahrenheit. Lightly grease your 22 by 33 centimeter baking dish to prevent sticking. Get out all your tools so everything is ready
Roast the Butternut Squash:
Toss the peeled and diced butternut squash with olive oil salt and pepper. Spread the cubes in a single layer on a baking sheet lined with parchment or foil. Roast for about twenty minutes stirring halfway so all sides brown a little. The squash should be fork tender with golden edges
Cook the Pasta:
Bring a large pot of salted water to a full rolling boil. Cook your pasta for two minutes less than the package suggests so it will finish in the oven. Drain it well but do not rinse so the sauce sticks properly
Make the Alfredo Sauce:
In a large saucepan melt the butter over medium heat. Add the finely chopped onion and cook for three to four minutes until soft and fragrant but not browned. Stir in the minced garlic and let it cook for just one more minute
Build the Cream Base:
Sprinkle in all-purpose flour and whisk constantly for about sixty seconds. This cooks out any raw flavor and forms the roux. Gradually pour in the milk and heavy cream whisking without stopping so the sauce stays smooth. Keep cooking and whisking four to five minutes until it thickens and coats the back of a spoon
Finish the Alfredo:
Remove the saucepan from the heat and add the grated Parmesan a pinch of salt cracked black pepper and just a small pinch of nutmeg. Stir until the cheese melts and the sauce is creamy without lumps
Combine Everything:
In a very large mixing bowl add the cooked pasta roasted squash and all the Alfredo sauce. Use a big spoon to toss gently until everything is evenly coated and combined. Be careful not to break up the squash too much
Assemble and Top:
Pour the mixture into your prepared baking dish and spread it evenly. Sprinkle the top with shredded mozzarella and the extra Parmesan cheese
Bake to Perfection:
Slide the dish into the hot oven and bake for twenty minutes. The cheese should be golden and bubbling on top and the sides gently sizzling. Let it rest for five minutes before scooping so the bake sets a little
Garnish and Serve:
Sprinkle the whole dish with plenty of fresh parsley if you want a bright color and herbal finish then serve hot to enjoy all that creamy cheddary goodness
Cheesy Alfredo Butternut Squash Pasta Bake featuring roasted squash – a savory vegetarian indulgence. Pin
Cheesy Alfredo Butternut Squash Pasta Bake featuring roasted squash – a savory vegetarian indulgence. | panpatriot.com

My favorite part is how the browned edges of the roasted squash turn almost nutty in flavor. I still remember making this for my grandmother and she smiled with each bite calling it pure comfort in a dish. It always reminds me of family gatherings and laughter in the kitchen.

Storage Tips

Leftovers keep well in the refrigerator for up to three days in an airtight container. For longer storage cool the pasta bake completely then wrap tightly and freeze up to two months. To reheat cover with foil and warm in a moderate oven until hot inside adding a splash of milk if it is looking dry.

Ingredient Substitutions

If you want to lighten the dish use half and half instead of heavy cream for the Alfredo. Goat cheese makes a delicious tangy substitute for some of the mozzarella on top. You can swap in other winter squash or even sweet potato. Gluten free pasta and flour blend work well if you need a wheat free version though the bake will be a little more tender.

Serving Suggestions

Serve portions with a crisp green salad to balance out the richness. Garlic bread or focaccia is a classic partner for soaking up any leftover creamy sauce. For a bigger spread add roasted broccoli or steamed green beans for extra color and nutrition.

Homemade Alfredo Butternut Squash Pasta Bake: creamy, cheesy goodness with tender squash and pasta. Pin
Homemade Alfredo Butternut Squash Pasta Bake: creamy, cheesy goodness with tender squash and pasta. | panpatriot.com

This creamy bake brings warmth to our table with every cheesy forkful. It is easy for beginners yet special enough for guests.

Recipe Questions

Can I use a different type of pasta?

Absolutely! Short shapes like fusilli or ziti work well and hold the creamy sauce beautifully.

How do I make this lighter?

Swap heavy cream for half-and-half, and use less cheese for a reduced fat version.

Can I add extra vegetables?

Yes, mix in sautéed mushrooms or spinach for more texture and flavor diversity.

Does this dish reheat well?

Reheat covered in the oven to preserve creaminess, or use the microwave for a quick option.

What cheeses work best for topping?

Mozzarella melts smoothly, while additional Parmesan adds extra savory depth and crispness.

Is this suitable for vegetarians?

Yes, it contains no meat and uses only vegetarian-friendly ingredients.

Alfredo Butternut Squash Pasta Bake

Comforting pasta bake with creamy Alfredo, roasted butternut squash, and bubbling cheese. Ideal for cozy nights.

Prep duration
20 min
Cooking duration
40 min
Total duration
60 min


Difficulty Easy

Origin Italian-American

Yield 4 Servings

Dietary requirements Vegetarian

Ingredients

Pasta

01 10 oz penne or rigatoni pasta

Vegetables

01 1 medium butternut squash (about 1.75 lbs), peeled and cut into ½ inch cubes
02 2 cloves garlic, minced
03 1 small yellow onion, finely chopped
04 1 tbsp olive oil

Alfredo Sauce

01 2 tbsp unsalted butter
02 2 tbsp all-purpose flour
03 1 ⅔ cups whole milk
04 ½ cup heavy cream
05 ¾ cup freshly grated Parmesan cheese
06 ½ tsp salt
07 ¼ tsp ground black pepper
08 Pinch ground nutmeg

Topping

01 1 cup shredded mozzarella cheese
02 ⅓ cup grated Parmesan cheese
03 2 tbsp chopped fresh parsley (optional)

Directions

Step 01

Oven Preparation: Preheat oven to 400°F and lightly grease a 9 x 13 inch baking dish.

Step 02

Roast Butternut Squash: Combine butternut squash cubes, olive oil, salt, and pepper. Spread on a baking sheet and roast for 20 minutes, stirring halfway, until tender and lightly golden.

Step 03

Cook Pasta: In a large pot of boiling salted water, cook pasta for 2 minutes less than package directions. Drain and set aside.

Step 04

Prepare Alfredo Base: In a large saucepan over medium heat, melt butter. Sauté onion for 3-4 minutes until softened, then add garlic and cook for 1 minute.

Step 05

Form Sauce: Stir in flour and cook for 1 minute. Gradually whisk in milk and heavy cream, continuing to stir until sauce is thickened, approximately 4-5 minutes.

Step 06

Finish Alfredo Sauce: Remove from heat and stir in Parmesan cheese, salt, black pepper, and nutmeg until sauce becomes smooth and creamy.

Step 07

Combine Elements: In a large mixing bowl, gently fold together cooked pasta, roasted butternut squash, and Alfredo sauce until thoroughly coated.

Step 08

Assemble: Transfer mixture to the greased baking dish, top evenly with mozzarella and additional Parmesan cheese.

Step 09

Bake: Bake for 20 minutes or until the cheese is golden and bubbling. Allow dish to rest for 5 minutes before serving. Garnish with fresh parsley if desired.

Necessary tools

  • Large saucepan
  • Baking sheet
  • Large pot
  • Mixing bowl
  • Whisk
  • 9 x 13 inch baking dish

Allergy information

Review each ingredient for potential allergens and consult with healthcare providers if you're uncertain.
  • Contains milk, butter, cream, and cheese (dairy allergens), and wheat gluten (pasta and flour).
  • Confirm ingredient labels for allergy safety when serving.

Nutrition facts (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Calories: 590
  • Fat: 25 g
  • Carbohydrates: 72 g
  • Protein: 21 g