Pizza Grilled Cheese Sandwich

Featured in: Game Day Snacks

Combining the best of two favorites, this pizza grilled cheese sandwich layers gooey mozzarella and zesty mini pepperoni between golden, buttery slices of bread. A touch of pizza sauce, fragrant oregano, and a sprinkle of parmesan create a savory filling that delivers satisfying flavor in every bite. Quick to prepare on the stovetop and perfect for dipping in extra warm sauce, this treat makes a crowd-pleasing lunch or snack for anyone craving comforting flavors and an irresistible cheesy pull.

Updated on Wed, 08 Oct 2025 12:14:12 GMT
Close-up of Pizza Grilled Cheese with gooey mozzarella, pepperoni, and golden toasted bread. Pin
Close-up of Pizza Grilled Cheese with gooey mozzarella, pepperoni, and golden toasted bread. | panpatriot.com

Pizza Grilled Cheese skips the pizza night delivery wait and delivers that gooey pepperoni delight in minutes. Think the nostalgic crunch of classic grilled cheese meets all the flavors of your favorite slice. It is irresistible for lunch cravers and late night snackers alike.

The first time I surprised my kids with this, their jaws dropped for a moment before they wolfed down everything in five minutes flat. Now, it is on our weekly “comfort meal” rotation.

Ingredients

  • Sandwich bread: This works best with sturdy classic white or whole wheat for the perfect crispy edge
  • Mozzarella cheese: Nothing beats the gooey melt and mild flavor mozzarella brings here Use a block and grate it for extra meltiness
  • Mini pepperoni: These little rounds fit perfectly and guarantee savory bites in every mouthful Opt for a good brand that is not greasy
  • Pizza sauce: Brings that unmistakable pizza tang Look for one that is thick so the bread does not get soggy
  • Parmesan cheese: This adds savory punch and nutty complexity Choose freshly grated if possible
  • Dried oregano: Classic pizza herb Sprinkle over the filling for authentic pizzeria aroma
  • Softened butter: Essential for golden crispy bread Choose unsalted to control saltiness or your preferred spread

Instructions

Prepare the Skillet:
Warm a large nonstick or cast iron skillet over medium heat Let it preheat for at least three minutes so your bread sears not steams
Butter the Bread:
Spread a generous layer of softened butter evenly over one side of each bread slice This ensures every bite crisps up perfectly
Layer the Sauce:
On the unbuttered side of two bread slices spoon just enough pizza sauce to coat without soaking the bread
Build the Cheese and Pepperoni Layer:
Scatter shredded mozzarella evenly across the pizza sauced sides Sprinkle mini pepperoni making sure you do not overcrowd Add a dusting of oregano and parmesan for maximum flavor
Assemble the Sandwich:
Place remaining bread slices buttered side out over fillings Press down gently to help fillings hold together
Grill the Sandwich:
Transfer sandwiches to the preheated skillet Cook three to four minutes per side pressing slightly with a spatula Check for deep golden toast and bubbling cheese before flipping
Rest and Serve:
Move sandwiches to a cutting board and wait one minute This step prevents cheese from spilling out Slice and plate while hot
Serve with Dipping Sauce:
Pour extra pizza sauce into a small bowl for dipping This turns every bite into a full pizza experience
Pizza Grilled Cheese sandwich sliced in half, revealing melted cheese and savory pizza sauce. Pin
Pizza Grilled Cheese sandwich sliced in half, revealing melted cheese and savory pizza sauce. | panpatriot.com

My wild card favorite ingredient here is a really rich pizza sauce Sometimes I sneak in fresh torn basil if I have it too My youngest once insisted this sandwich felt as special as a pizza party night only mess free

Storage Tips

Pizza grilled cheese is best eaten hot right from the pan but leftovers will keep in an airtight container for up to two days To reheat use the skillet again not the microwave to maintain crispness A quick toast revives the crunch

Ingredient Substitutions

No mozzarella Try provolone or monterey jack for good melt Vegan cheese and plant based pepperoni turn this into a dairy free treat Switch up the sauce for pesto or tomato paste if you want deeper flavor

Serving Suggestions

Pair with a green salad or a roasted veggie soup for a full meal Cut sandwiches into strips for easy dipping at parties My kids love it with a side of carrot sticks and that extra pizza sauce

Plated Pizza Grilled Cheese served hot with a side of marinara dipping sauce. Pin
Plated Pizza Grilled Cheese served hot with a side of marinara dipping sauce. | panpatriot.com

No matter how you slice it pizza grilled cheese is a true crowd pleaser that welcomes little tweaks and always satisfies any pizza craving

Recipe Questions

What type of bread works best?

Sandwich bread is ideal for holding in the fillings and getting a crispy crust, but sourdough or Italian bread also works well.

Can I use different cheeses?

Yes, try provolone or a blend with mozzarella for extra flavor and gooeyness.

Is it possible to make this vegetarian?

Absolutely! Simply omit the pepperoni or use vegetarian alternatives.

How do I prevent soggy bread?

Butter the outside of the bread slices and avoid adding too much pizza sauce inside to keep it crisp.

What can I serve alongside this sandwich?

Extra pizza sauce for dipping works great, or pair with a simple green salad or chips.

Pizza Grilled Cheese Sandwich

Classic grilled cheese meets pizza for a melty, savory sandwich with mozzarella and pepperoni.

Prep duration
5 min
Cooking duration
8 min
Total duration
13 min

Category Game Day Snacks

Difficulty Easy

Origin American

Yield 2 Servings

Dietary requirements None specified

Ingredients

Main Components

01 4 slices sandwich bread
02 2 tablespoons unsalted butter, softened

Cheese & Toppings

01 1/2 cup shredded mozzarella cheese
02 1/4 cup mini pepperoni slices
03 2 tablespoons grated parmesan cheese
04 1/2 teaspoon dried oregano

Sauce

01 1/4 cup pizza sauce, plus extra for serving

Directions

Step 01

Preheat Cooking Surface: Set a skillet over medium heat and allow it to preheat.

Step 02

Prepare Bread: Evenly spread the softened butter on one side of each bread slice.

Step 03

Add Sauce Layer: On the unbuttered side of two bread slices, spread pizza sauce in a thin, even layer.

Step 04

Assemble Filling: Distribute shredded mozzarella, mini pepperoni slices, a pinch of dried oregano, and a sprinkling of parmesan cheese over the sauced sides.

Step 05

Top Sandwiches: Place the remaining bread slices on top, buttered side out, to form two sandwiches.

Step 06

Cook Sandwiches: Transfer assembled sandwiches to the preheated skillet. Cook for 3 to 4 minutes per side, pressing gently, until the exterior is golden brown and the cheese is fully melted.

Step 07

Rest and Slice: Remove sandwiches from heat and let them rest for 1 minute before slicing.

Step 08

Serve: Serve warm, accompanied by additional pizza sauce for dipping.

Necessary tools

  • Nonstick skillet or frying pan
  • Spatula
  • Measuring cups and spoons
  • Bread knife

Allergy information

Review each ingredient for potential allergens and consult with healthcare providers if you're uncertain.
  • Contains gluten, dairy, and may contain pork allergens.

Nutrition facts (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Calories: 467
  • Fat: 27 g
  • Carbohydrates: 39 g
  • Protein: 18 g